Manny is a Pre-Madonna The reason Youkilis and Manny got into it was because Youkilis called Man-Ram out for not leaving the bench to help participate in the fight early on in the game against the Rays.

Manny probably got pissed at Youkilis for calling him a “sissy” then decides to pummel Youkilis instead of the Rays (like he should have in the first place).